When anyone is looking for the best labs that offer monoclonal antibody production, they expect the capacity to provide customized services. This type of company has extensive experience producing thousands of custom monoclonal antibodies with high specificity and high affinity. Their teams have the capability and expertise to manage large-scale antibody production.
Producing Monoclonal Antibodies
Monoclonal antibody production is a critical part of research and treatment for many infectious and noninfectious diseases. Companies that design and offer custom monoclonal antibody production understand the range of benefits, including treating certain types of cancer, research, diagnostics, and product development. One option is hybridoma monoclonal antibody production services, and they can accept clients’ other cell lines for antibody production as well. They have a team of scientists on staff who can provide antibodies that are tailored to the customer specification.
Standard Monoclonal Antibody Production
The traditional process for monoclonal antibody production involved immunizing mice, producing hybridomas, screening the clones, and scaling up the clone production. However, the best cell culture companies offer an alternative that is easy to scale. It is a perfusion-based bioreactor approach where cells are cultured to inoculate a single-use hollow fiber cartridge. There is a consistent flow of media that delivers nutrients across the semipermeable fibers. This environment is a bioreactor type, and it is constantly monitored and maintained at ideal conditions for production of antibodies. It produces a continuous and concentrated stream of product that can be harvested over several weeks to several months. This allows the company to produce more products for their clients.
